Randomized studies are still necessary

Are Histologic Studies of Adenotonsillectomy Really Necessary?

Introduction In most ear, nose, and throat services, it is routine to send the material extracted from tonsillectomy for histologic study to research malignancy, to analyze suspect material, or to provide medical-legal documentation. Recent studies have shown that this routine analysis is dispensable. Objective To evaluate the actual need and perform a cost-benefit analysis of routine histopath...

Pathology: is it still necessary?

One may wonder what may be the reasons to ask this apparently odd question. Undoubtedly, the main concern is that we are still far away from being able to precisely identify the target population of patients for tailored interventions. It has been repeatedly shown by the results of large clinical trials that the benefit of new therapeutic approaches is relatively small, and that it is most like...

Is breast self-examination still necessary?

Why animal studies are still being used in drug development.

In the European Union, about 3.6 million animals per year (30% of all the animals used) are used for drug development.1 Animal studies are the global standard used to evaluate the safety, efficacy and quality of drugs before these drugs are tested in humans. However, the value of animal studies to predict risks for humans has never been extensively established.2 In fact, many studies indicate t...

Is antenatal screening for syphilis still necessary?